STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa)    
Predicted Functional Partners:
ESK65527.1
Threonine synthase; KEGG: smu:SMU.70 5.2e-151 thrC; putative threonine synthase K01733.
 
 0.998
ESK64850.1
KEGG: btk:BT9727_1799 4.2e-78 hom; homoserine dehydrogenase K00003.
 
 0.998
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: oih:OB0747 1.1e-100 phosphoribosylaminoimidazole synthetase K01933; Psort location: Cytoplasmic, score: 8.96.
 
    
 0.912
ESK64851.1
KEGG: gka:GK3195 3.5e-113 aspartate kinase K00928; Belongs to the aspartokinase family.
 
 
 0.904
ESK66107.1
Branched-chain-amino-acid transaminase; KEGG: pmu:PM0566 3.8e-132 ivlE; branched-chain amino acid aminotransferase K00826.
  
 
 0.871
ESK65922.1
Putative cystathionine beta-lyase; KEGG: lla:L0102 4.4e-106 metB1; cystathionine gamma-synthase K01739; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.870
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.847
ESK66210.1
Putative serine O-acetyltransferase; KEGG: hac:Hac_0304 2.3e-45 cysE; hypothetical protein K00640; Psort location: Cytoplasmic, score: 9.26.
     
 0.842
ESK65409.1
KEGG: btl:BALH_2934 1.3e-51 sdhB; L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752.
  
 
 0.837
SdaAA
KEGG: efa:EF0099 3.9e-98 sdhA-1; L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752.
  
 
 0.837
Your Current Organism:
Abiotrophia defectiva
NCBI taxonomy Id: 592010
Other names: A. defectiva ATCC 49176, Abiotrophia defectiva ATCC 49176, Abiotrophia defectiva str. ATCC 49176, Abiotrophia defectiva strain ATCC 49176
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