STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESK64873.1KEGG: sab:SAB2369c 2.9e-125 DNA modification methylase K00558; Psort location: Cytoplasmic, score: 8.96. (406 aa)    
Predicted Functional Partners:
Dcm
KEGG: mpe:MYPE4940 2.0e-39 cytosine-specific DNA methyltransferase K00558; Psort location: Cytoplasmic, score: 8.96.
 
  
 
0.958
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.921
MtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.901
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.901
ESK64872.1
Hypothetical protein.
     
 0.781
ESK64871.1
Hypothetical protein.
 
  
 0.754
ESK64781.1
KEGG: spn:SP_1168 4.3e-60 mutator MutT protein K01529; Psort location: Cytoplasmic, score: 8.96; Belongs to the Nudix hydrolase family.
 
      0.695
ESK64867.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
     
 0.492
ESK64870.1
Hypothetical protein.
       0.479
ESK64868.1
Hypothetical protein.
       0.466
Your Current Organism:
Abiotrophia defectiva
NCBI taxonomy Id: 592010
Other names: A. defectiva ATCC 49176, Abiotrophia defectiva ATCC 49176, Abiotrophia defectiva str. ATCC 49176, Abiotrophia defectiva strain ATCC 49176
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.