STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESK64878.1Transaldolase; KEGG: sph:MGAS10270_Spy1729 8.4e-96 transaldolase K00616; Psort location: Cytoplasmic, score: 8.96. (238 aa)    
Predicted Functional Partners:
Tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.984
pgi
KEGG: efa:EF1416 2.1e-177 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.26; Belongs to the GPI family.
  
 
 0.965
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.928
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
 0.925
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.920
ESK66222.1
KEGG: sto:ST2030 8.5e-32 triosephosphate isomerase (TIM) K01803.
  
 0.915
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.902
Pyk
Pyruvate kinase; KEGG: efa:EF1046 1.8e-210 pyk; pyruvate kinase K00873; Belongs to the pyruvate kinase family.
  
 
 0.902
Gap
KEGG: efa:EF1964 3.8e-155 gap-2; glyceraldehyde 3-phosphate dehydrogenases K00134; Psort location: Cytoplasmic, score: 9.97; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.900
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.870
Your Current Organism:
Abiotrophia defectiva
NCBI taxonomy Id: 592010
Other names: A. defectiva ATCC 49176, Abiotrophia defectiva ATCC 49176, Abiotrophia defectiva str. ATCC 49176, Abiotrophia defectiva strain ATCC 49176
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