STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT35515.1KEGG: aco:Amico_0078 9.1e-80 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752; Psort location: Cytoplasmic, score: 9.26. (294 aa)    
Predicted Functional Partners:
KRT35514.1
KEGG: tai:Taci_0266 2.1e-71 L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752.
  
  0.999
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.909
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.908
KRT35520.1
CDP-diacylglycerol-serine O-phosphatidyltransferase; KEGG: aco:Amico_0254 6.5e-70 CDP-diacylglycerol/serineO-phosphatidyl transferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.889
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.861
KRT35301.1
KEGG: tai:Taci_1720 4.0e-93 pyridoxal-5'-phosphate-dependent protein beta subunit; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.857
KRT35058.1
KEGG: aco:Amico_0097 4.7e-60 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97.
     
 0.850
KRT34874.1
Aminotransferase, class V; KEGG: dhd:Dhaf_4850 1.7e-78 alanine--glyoxylate transaminase; Psort location: Cytoplasmic, score: 9.97.
    
 0.842
KRT35035.1
KEGG: aco:Amico_0491 1.4e-76 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 9.97.
   
 
  0.842
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.834
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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