STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT35517.1Nitroreductase family protein; KEGG: mma:MM_3268 4.6e-37 NADPH-flavin oxidoreductase; K00358. (203 aa)    
Predicted Functional Partners:
KRT35962.1
KEGG: tai:Taci_0812 5.6e-32 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97.
  
    0.772
KRT35483.1
ABC-2 type transporter; KEGG: phu:Phum_PHUM026790 1.0e-10 ABC transporter, putative; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.763
KRT34982.1
AMP-binding enzyme; KEGG: tai:Taci_1674 3.2e-100 AMP-dependent synthetase and ligase; K01897 long-chain acyl-CoA synthetase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.728
KRT35516.1
Hypothetical protein; KEGG: mma:MM_0687 2.2e-14 nitrogenase iron protein K07321; Psort location: Cytoplasmic, score: 8.96.
       0.701
KRT35286.1
Nitroreductase family protein; KEGG: dth:DICTH_0759 3.8e-17 NADH dehydrogenase (h(2)o(2) forming nadh oxidase); Psort location: Cytoplasmic, score: 9.97.
  
     0.700
KRT35247.1
methylmalonyl-CoA epimerase; KEGG: tte:TTE2386 2.0e-45 gloA3; lactoylglutathione lyase and related lyase; K01759 lactoylglutathione lyase; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.582
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.570
KRT35514.1
KEGG: tai:Taci_0266 2.1e-71 L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752.
       0.550
KRT35515.1
KEGG: aco:Amico_0078 9.1e-80 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752; Psort location: Cytoplasmic, score: 9.26.
       0.550
KRT36468.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: tde:TDE0153 1.7e-197 coenzyme A disulfide reductase, putative; K00359 NADH oxidase; Psort location: Cytoplasmic, score: 9.97.
    
 0.530
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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