node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT34923.1 | recR | HMPREF1705_04175 | HMPREF1705_03438 | KEGG: tai:Taci_1436 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.649 |
KRT34923.1 | topA | HMPREF1705_04175 | HMPREF1705_02830 | KEGG: tai:Taci_1436 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.991 |
KRT34923.1 | xerC | HMPREF1705_04175 | HMPREF1705_02832 | KEGG: tai:Taci_1436 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96. | Phage integrase, SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.691 |
KRT35593.1 | KRT35597.1 | HMPREF1705_02829 | HMPREF1705_02833 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.655 |
KRT35593.1 | KRT35860.1 | HMPREF1705_02829 | HMPREF1705_03115 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: chu:CHU_3495 4.7e-06 purF; amidophosphoribosyltransferase K00764. | 0.845 |
KRT35593.1 | codY | HMPREF1705_02829 | HMPREF1705_02836 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.567 |
KRT35593.1 | hslU | HMPREF1705_02829 | HMPREF1705_02834 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.597 |
KRT35593.1 | recR | HMPREF1705_02829 | HMPREF1705_03438 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.564 |
KRT35593.1 | rnhB | HMPREF1705_02829 | HMPREF1705_02822 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.828 |
KRT35593.1 | topA | HMPREF1705_02829 | HMPREF1705_02830 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.968 |
KRT35593.1 | trmFO | HMPREF1705_02829 | HMPREF1705_02831 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.819 |
KRT35593.1 | xerC | HMPREF1705_02829 | HMPREF1705_02832 | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | Phage integrase, SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.773 |
KRT35597.1 | KRT35593.1 | HMPREF1705_02833 | HMPREF1705_02829 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | 0.655 |
KRT35597.1 | codY | HMPREF1705_02833 | HMPREF1705_02836 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.824 |
KRT35597.1 | hslU | HMPREF1705_02833 | HMPREF1705_02834 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.999 |
KRT35597.1 | rnhB | HMPREF1705_02833 | HMPREF1705_02822 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.597 |
KRT35597.1 | topA | HMPREF1705_02833 | HMPREF1705_02830 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.757 |
KRT35597.1 | trmFO | HMPREF1705_02833 | HMPREF1705_02831 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.705 |
KRT35597.1 | xerC | HMPREF1705_02833 | HMPREF1705_02832 | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Phage integrase, SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.884 |
KRT35860.1 | KRT35593.1 | HMPREF1705_03115 | HMPREF1705_02829 | Hypothetical protein; KEGG: chu:CHU_3495 4.7e-06 purF; amidophosphoribosyltransferase K00764. | KEGG: apb:SAR116_0616 2.3e-37 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 8.96. | 0.845 |