STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT35665.1Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (411 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.998
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.992
KRT35664.1
Putative arabinose 5-phosphate isomerase; KEGG: aco:Amico_1493 2.1e-105 KpsF/GutQ family protein K06041; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.976
KRT34908.1
KEGG: aco:Amico_0413 1.2e-61 lipid A biosynthesis acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.964
KRT35537.1
KEGG: aco:Amico_0274 1.2e-79 lipid A biosynthesis acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.961
KRT34630.1
Lipopolysaccharide heptosyltransferase II; KEGG: aco:Amico_1486 5.8e-85 glycosyl transferase family 9; K02843 heptosyltransferase II; Psort location: Cytoplasmic, score: 9.26.
  
 0.955
kdsA
3-deoxy-8-phosphooctulonate synthase; KEGG: aco:Amico_1494 7.0e-89 2-dehydro-3-deoxyphosphooctonate aldolase; K01627 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family.
 
   
 0.954
KRT34401.1
O-antigen polymerase; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.870
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.864
KRT35653.1
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.863
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.