node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT35314.1 | KRT36312.1 | HMPREF1705_04585 | HMPREF1705_03588 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | 0.977 |
KRT35314.1 | dnaG | HMPREF1705_04585 | HMPREF1705_03017 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.594 |
KRT35314.1 | rpoB | HMPREF1705_04585 | HMPREF1705_03055 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.423 |
KRT35314.1 | sigA | HMPREF1705_04585 | HMPREF1705_03018 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.745 |
KRT36312.1 | KRT35314.1 | HMPREF1705_03588 | HMPREF1705_04585 | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.977 |
KRT36312.1 | dnaG | HMPREF1705_03588 | HMPREF1705_03017 | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.597 |
KRT36312.1 | rpoA | HMPREF1705_03588 | HMPREF1705_03094 | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.902 |
KRT36312.1 | rpoB | HMPREF1705_03588 | HMPREF1705_03055 | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.939 |
KRT36312.1 | rpoC | HMPREF1705_03588 | HMPREF1705_03057 | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.927 |
KRT36312.1 | rpoZ | HMPREF1705_03588 | HMPREF1705_03511 | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.902 |
KRT36312.1 | sigA | HMPREF1705_03588 | HMPREF1705_03018 | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.916 |
KRT36468.1 | groL | HMPREF1705_03749 | HMPREF1705_03010 | Pyridine nucleotide-disulfide oxidoreductase; KEGG: tde:TDE0153 1.7e-197 coenzyme A disulfide reductase, putative; K00359 NADH oxidase; Psort location: Cytoplasmic, score: 9.97. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.589 |
KRT36468.1 | sigA | HMPREF1705_03749 | HMPREF1705_03018 | Pyridine nucleotide-disulfide oxidoreductase; KEGG: tde:TDE0153 1.7e-197 coenzyme A disulfide reductase, putative; K00359 NADH oxidase; Psort location: Cytoplasmic, score: 9.97. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.796 |
dnaG | KRT35314.1 | HMPREF1705_03017 | HMPREF1705_04585 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.594 |
dnaG | KRT36312.1 | HMPREF1705_03017 | HMPREF1705_03588 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Hypothetical protein; KEGG: sce:YML061C 1.7e-46 PIF1, TST1; DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA; Psort location: Cytoplasmic, score: 8.96. | 0.597 |
dnaG | nusA | HMPREF1705_03017 | HMPREF1705_03517 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.648 |
dnaG | rpoA | HMPREF1705_03017 | HMPREF1705_03094 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.499 |
dnaG | rpoB | HMPREF1705_03017 | HMPREF1705_03055 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.527 |
dnaG | rpoC | HMPREF1705_03017 | HMPREF1705_03057 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.566 |
dnaG | sigA | HMPREF1705_03017 | HMPREF1705_03018 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.996 |