STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (414 aa)    
Predicted Functional Partners:
KRT35559.1
KEGG: tai:Taci_0141 1.9e-196 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.968
KRT36132.1
KEGG: mta:Moth_0963 2.2e-78 amidohydrolase; K12960 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Psort location: Cytoplasmic, score: 9.97.
 
    0.894
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.882
KRT35057.1
KEGG: tai:Taci_1734 6.3e-88 cysteine synthase; K01738 cysteine synthase A; Psort location: CytoplasmicMembrane, score: 8.46.
  
 0.870
KRT35564.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: tai:Taci_1506 1.0e-135 O-acetylhomoserineaminocarboxypropyltransferase K01740; Psort location: Cytoplasmic, score: 9.97.
     
 0.861
KRT34528.1
Pyridoxal-phosphate dependent protein; KEGG: clj:CLJU_c08270 3.7e-177 cysteine synthase; Psort location: Cytoplasmic, score: 8.96.
  
 0.848
KRT35301.1
KEGG: tai:Taci_1720 4.0e-93 pyridoxal-5'-phosphate-dependent protein beta subunit; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.846
KRT35035.1
KEGG: aco:Amico_0491 1.4e-76 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 9.97.
   
 
  0.841
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.820
KRT34894.1
KEGG: aco:Amico_0287 4.0e-70 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 9.97.
   
 
  0.814
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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