STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT36146.1Phage integrase, SAM-like domain protein; KEGG: apb:SAR116_1837 2.1e-32 phage integrase family protein K03733; Psort location: Cytoplasmic, score: 9.97; Belongs to the 'phage' integrase family. (299 aa)    
Predicted Functional Partners:
KRT36148.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
       0.824
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
  
    0.794
KRT34923.1
KEGG: tai:Taci_1436 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
    
  0.691
KRT35860.1
Hypothetical protein; KEGG: chu:CHU_3495 4.7e-06 purF; amidophosphoribosyltransferase K00764.
   
    0.683
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.658
KRT36144.1
KEGG: aco:Amico_1016 1.7e-53 pyruvate/ketoisovalerate oxidoreductase; K00177 2-oxoglutarate ferredoxin oxidoreductase subunit gamma.
    
  0.620
KRT36143.1
KEGG: aco:Amico_1017 3.6e-101 thiamine pyrophosphate protein domain protein TPP-binding protein; K00175 2-oxoglutarate ferredoxin oxidoreductase subunit beta; Psort location: Cytoplasmic, score: 8.96.
    
  0.607
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.594
KRT36142.1
3-methyl-2-oxobutanoate dehydrogenase; KEGG: aco:Amico_1018 2.4e-120 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; K00174 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Psort location: Cytoplasmic, score: 8.96.
    
  0.583
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.567
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
Server load: low (24%) [HD]