STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT36149.1ThiF family protein; KEGG: hpa:HPAG1_0799 3.3e-27 thiamine biosynthesis protein; Psort location: Cytoplasmic, score: 9.97. (277 aa)    
Predicted Functional Partners:
KRT35910.1
MoaD family protein.
  
 0.992
KRT36263.1
ThiS family protein.
  
 0.987
KRT34616.1
Thiamine biosynthesis protein ThiS.
  
 0.987
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.906
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.884
KRT36292.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.868
KRT35575.1
KEGG: ddf:DEFDS_1615 1.2e-132 thiC; thiamine biosynthesis protein ThiC K03147; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.842
KRT35250.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
   
 0.837
KRT34813.1
Phosphomethylpyrimidine kinase; KEGG: cpo:COPRO5265_0004 2.3e-99 thiD; phosphomethylpyrimidine kinase K00941; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.831
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.795
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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