STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (674 aa)    
Predicted Functional Partners:
KRT36193.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.999
KRT36153.1
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
 
 0.997
KRT34561.1
Putative ATP-dependent helicase PcrA; KEGG: aco:Amico_1179 3.0e-184 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.969
KRT36194.1
KEGG: aco:Amico_0782 1.4e-49 RNA methyltransferase, TrmH family, group 3; K03218 RNA methyltransferase, TrmH family; Psort location: Cytoplasmic, score: 9.26; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
     
 0.844
KRT36197.1
FtsK/SpoIIIE family protein; KEGG: eci:UTI89_C0905 1.0e-99 ftsK; DNA translocase FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the FtsK/SpoIIIE/SftA family.
     
 0.829
KRT35383.1
N-6 DNA Methylase; KEGG: bts:Btus_2963 1.7e-298 N-6 DNA methylase; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 8.96.
    
 
 0.778
KRT36195.1
Hypothetical protein.
       0.773
KRT36196.1
TldD/PmbA family protein; KEGG: eci:UTI89_C3675 2.4e-72 tldD; protease TldD K03568; Psort location: Cytoplasmic, score: 9.97.
       0.773
KRT36198.1
KEGG: aco:Amico_0854 2.2e-44 thiamine pyrophosphokinase; K00949 thiamine pyrophosphokinase.
       0.773
KRT36199.1
Hypothetical protein.
       0.773
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.