Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadKInorganic polyphosphate/ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (293 aa)    
Predicted Functional Partners:
KRT36205.1
Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
 0.933
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.921
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.904
KRT36203.1
Ribosomal RNA large subunit methyltransferase J; KEGG: rcm:A1E_02195 1.4e-44 tyrosyl-tRNA synthetase K06442; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.890
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
 
  
 0.886
KRT34941.1
Putative NAD-dependent deacetylase; KEGG: pmo:Pmob_1359 2.2e-78 silent information regulator protein Sir2; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.823
KRT36469.1
Hydrolase, NUDIX family; KEGG: mma:MM_2542 3.4e-57 phosphohydrolase; K03426 NAD+ diphosphatase.
     
 0.784
KRT36009.1
Putative protein MazG; KEGG: aco:Amico_0750 6.1e-74 MazG family protein; K02428 nucleoside-triphosphate pyrophosphatase; Psort location: Cytoplasmic, score: 8.96.
     
  0.783
KRT36201.1
KEGG: aco:Amico_0851 3.7e-67 geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.97; Belongs to the FPP/GGPP synthase family.
 
 
 
 0.677
KRT34968.1
Molybdopterin binding domain protein; KEGG: cco:CCC13826_0279 1.5e-21 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family.
  
 
 0.605
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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