STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT36242.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa)    
Predicted Functional Partners:
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
 
 0.988
KRT36243.1
KEGG: aco:Amico_1081 2.5e-125 primosomal protein N' (replication factor Y) - superfamily II helicase-like protein; K04066 primosomal protein N' (replication factor Y) (superfamily II helicase); Psort location: Cytoplasmic, score: 8.96.
 
    0.960
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.907
coaX
Putative pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
 
 0.897
KRT34565.1
Putative aspartate transaminase; KEGG: aco:Amico_1183 1.4e-124 aminotransferase class I and II; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97.
  
  0.866
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.865
KRT35057.1
KEGG: tai:Taci_1734 6.3e-88 cysteine synthase; K01738 cysteine synthase A; Psort location: CytoplasmicMembrane, score: 8.46.
    
  0.841
KRT35881.1
Putative cystathionine beta-lyase PatB; KEGG: aco:Amico_0119 4.1e-100 aminotransferase class I and II; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97.
    
  0.829
KRT34816.1
Hydrolase, NUDIX family; KEGG: noc:Noc_1415 8.2e-31 NUDIX hydrolase K01518; Psort location: Cytoplasmic, score: 8.96.
  
 
  0.828
KRT34528.1
Pyridoxal-phosphate dependent protein; KEGG: clj:CLJU_c08270 3.7e-177 cysteine synthase; Psort location: Cytoplasmic, score: 8.96.
    
  0.814
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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