STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT36362.1Phospholipase D domain protein; KEGG: reu:Reut_A2710 1.7e-76 cardiolipin synthetase 2 K06131; Psort location: CytoplasmicMembrane, score: 7.88; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (465 aa)    
Predicted Functional Partners:
KRT34550.1
Fe-S iron-sulfur cluster assembly protein, NifU family; KEGG: rxy:Rxyl_1354 1.6e-20 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566; Psort location: Cytoplasmic, score: 9.26.
   
 
 0.931
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.870
KRT36361.1
Endonuclease/exonuclease/phosphatase family protein; KEGG: bme:BMEII0240 3.2e-05 dioxygenase K06896; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.864
KRT34969.1
KEGG: aco:Amico_0391 1.9e-38 phosphatidylglycerophosphatase A; K01095 phosphatidylglycerophosphatase A; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.861
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
    
  0.805
KRT35701.1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: tai:Taci_0640 5.0e-63 CDP-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.694
KRT36236.1
Acyltransferase; KEGG: aco:Amico_1088 6.4e-47 phospholipid/glycerol acyltransferase; K00655 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.680
KRT36363.1
Transporter, major facilitator family protein; KEGG: hse:Hsero_0990 2.5e-25 mmr; methylenomycin A resistance protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.674
plsY-2
Phosphatidate cytidylyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
 
  
 0.666
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.648
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.