STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT34691.1Hypothetical protein; KEGG: ddd:Dda3937_01593 2.0e-05 prophage Clp protease-like protein; Psort location: CytoplasmicMembrane, score: 9.93. (278 aa)    
Predicted Functional Partners:
KRT34692.1
KEGG: cbi:CLJ_B3821 2.2e-259 clpC; negative regulator of genetic competence MecB/ClpC K03696; Psort location: Cytoplasmic, score: 9.97; Belongs to the ClpA/ClpB family.
  
  
 0.627
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.484
KRT34693.1
ATP:guanido phosphotransferase, catalytic domain protein; KEGG: bbe:BBR47_01870 8.2e-79 mcsB; modulator of CtsR repression protein; Psort location: Cytoplasmic, score: 8.96.
       0.477
KRT34694.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.477
KRT34695.1
Firmicute transcriptional repressor of class III stress; Psort location: Cytoplasmic, score: 8.96.
       0.470
KRT34690.1
Na+/H+ antiporter NhaC; KEGG: apb:SAR116_0021 0.00029 major facilitator family transporter; Psort location: CytoplasmicMembrane, score: 10.00.
       0.420
KRT35370.1
Transporter, major facilitator family protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.408
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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