STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT34813.1Phosphomethylpyrimidine kinase; KEGG: cpo:COPRO5265_0004 2.3e-99 thiD; phosphomethylpyrimidine kinase K00941; Psort location: Cytoplasmic, score: 8.96. (270 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
thiM
Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
 
 0.999
KRT35254.1
TENA/THI-4 family protein; KEGG: npu:Npun_R3311 6.3e-56 TenA family transcription regulator; K03707 thiaminase (transcriptional activator TenA).
 
 0.998
KRT35575.1
KEGG: ddf:DEFDS_1615 1.2e-132 thiC; thiamine biosynthesis protein ThiC K03147; Psort location: Cytoplasmic, score: 9.97.
 
 0.994
KRT36263.1
ThiS family protein.
  
 
  0.870
KRT34616.1
Thiamine biosynthesis protein ThiS.
  
 
  0.870
thi4
Thiazole biosynthesis enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
  
  
 0.841
KRT36149.1
ThiF family protein; KEGG: hpa:HPAG1_0799 3.3e-27 thiamine biosynthesis protein; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.831
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
  
    0.755
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
    0.725
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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