STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (291 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 0.996
ilvD
KEGG: afn:Acfer_1425 5.9e-163 dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 9.97; Belongs to the IlvD/Edd family.
  
 0.971
ilvD-2
KEGG: tte:TTE0020 6.3e-191 ilvD; dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 9.97; Belongs to the IlvD/Edd family.
  
 0.945
KRT35066.1
Aminotransferase, class IV; KEGG: aco:Amico_1844 8.8e-66 aminotransferase class IV; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 9.97.
 
  
 
0.918
KRT35184.1
KEGG: dtu:Dtur_1641 3.9e-72 prephenate dehydratase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.891
KRT35035.1
KEGG: aco:Amico_0491 1.4e-76 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.890
KRT34923.1
KEGG: tai:Taci_1436 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.878
KRT35301.1
KEGG: tai:Taci_1720 4.0e-93 pyridoxal-5'-phosphate-dependent protein beta subunit; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.877
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.842
KRT34894.1
KEGG: aco:Amico_0287 4.0e-70 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.807
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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