STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT35117.11-phosphofructokinase; KEGG: meh:M301_1126 4.1e-68 1-phosphofructokinase; K00882 1-phosphofructokinase; Psort location: Cytoplasmic, score: 9.97; Belongs to the carbohydrate kinase PfkB family. (314 aa)    
Predicted Functional Partners:
KRT35119.1
Putative PTS system fructose-specific EIIBBC component; KEGG: tai:Taci_1717 8.2e-166 PTS system, fructose subfamily, IIC subunit; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.999
KRT35118.1
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: gka:GK1838 1.1e-30 PTS system, fructose-specific enzyme II, BC component; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: Cytoplasmic, score: 9.26.
 
 
 0.982
KRT35116.1
Transcriptional regulator, DeoR family; KEGG: apb:SAR116_0891 2.6e-27 glycerol-3-phosphate regulon repressor K02444; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.969
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.891
KRT35988.1
Low molecular weight phosphotyrosine protein phosphatase; KEGG: dae:Dtox_4179 3.4e-15 protein tyrosine phosphatase; K01104 protein-tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.872
KRT35884.1
Ketose-bisphosphate aldolase; KEGG: gme:Gmet_2383 1.9e-63 fructose-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.860
KRT35985.1
Hexose kinase, 1-phosphofructokinase family; KEGG: aco:Amico_0728 2.8e-92 1-phosphofructokinase; K00882 1-phosphofructokinase; Psort location: Cytoplasmic, score: 9.97; Belongs to the carbohydrate kinase PfkB family.
  
  
 
0.853
KRT34865.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.825
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.820
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.820
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.