STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panB-33-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (294 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.784
KRT35222.1
Aminotransferase, class I/II; KEGG: aco:Amico_0368 1.5e-125 aminotransferase class I and II; K00811 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.749
fbp
Fructose-1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
       0.648
KRT35223.1
Asp/Glu/Hydantoin racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.520
ilvE
Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.505
KRT35066.1
Aminotransferase, class IV; KEGG: aco:Amico_1844 8.8e-66 aminotransferase class IV; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 9.97.
     
 0.505
KRT35962.1
KEGG: tai:Taci_0812 5.6e-32 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.474
KRT35224.1
Peptidase; KEGG: cbl:CLK_2276 5.9e-53 peptidase; Psort location: Cytoplasmic, score: 9.97.
       0.471
KRT35225.1
Amino acid carrier protein; KEGG: pmj:P9211_06131 6.1e-74 Na+/alanine symporter K03310; Psort location: CytoplasmicMembrane, score: 10.00.
       0.452
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.414
Your Current Organism:
Acetomicrobium hydrogeniformans
NCBI taxonomy Id: 592015
Other names: A. hydrogeniformans ATCC BAA-1850, Acetomicrobium hydrogeniformans ATCC BAA-1850, Anaerobaculum hydrogeniforman DSM 22491, Anaerobaculum hydrogeniforman OS1, Anaerobaculum sp. OS1
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