STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESL03958.1KEGG: bth:BT2048 4.6e-24 dihydrofolate reductase K00287; Psort location: Cytoplasmic, score: 8.87. (165 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.928
fhs
KEGG: chy:CHY_2385 5.0e-201 fhs; formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.925
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
 
 0.925
ESL02932.1
AICARFT/IMPCHase bienzyme; KEGG: xtr:448061 4.5e-120 atic; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase K00602:K01492; Psort location: Cytoplasmic, score: 8.87.
    
 0.921
ESL02406.1
Hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.921
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
   
 
 0.920
ESL02826.1
Ribose-5-phosphate isomerase B; KEGG: cno:NT01CX_0543 3.0e-43 rpiB; ribose 5-phosphate isomerase B K01806; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.760
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.613
ESL03959.1
KEGG: ava:Ava_0243 0.0032 molybdate ABC transporter, permease protein K02018; Psort location: CytoplasmicMembrane, score: 10.00.
       0.610
ESL03960.1
KEGG: cyb:CYB_0398 0.00047 modB; molybdate ABC transporter, permease protein K02018; Psort location: CytoplasmicMembrane, score: 10.00.
       0.610
Your Current Organism:
Catonella morbi
NCBI taxonomy Id: 592026
Other names: C. morbi ATCC 51271, Catonella morbi ATCC 51271, Catonella morbi str. ATCC 51271, Catonella morbi strain ATCC 51271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.