STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa)    
Predicted Functional Partners:
ESL03779.1
NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 5.3e-78 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; Psort location: Cytoplasmic, score: 8.87.
   
 0.992
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 0.976
ESL04271.1
Hypothetical protein; KEGG: lsl:LSL_0129 1.1e-08 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549; Psort location: Extracellular, score: 8.82.
  
 0.975
ESL03140.1
Putative aspartate transaminase; KEGG: tte:TTE2440 2.3e-125 avtA4; PLP-dependent aminotransferases K00821; Psort location: Cytoplasmic, score: 8.87.
  
 0.935
ESL02736.1
KEGG: sps:SPs0136 4.7e-118 putative cystathionine beta-lyase K01760; Psort location: Cytoplasmic, score: 9.98.
   
 0.926
ESL02920.1
KEGG: cje:Cj1202 8.8e-69 metF; 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.875
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.873
ESL04112.1
C-5 cytosine-specific DNA methylase; KEGG: ngo:NGO1894 1.4e-17 putative 5-methylcytosine methyltransferase K00558; Psort location: CytoplasmicMembrane, score: 9.75; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.836
ESL03994.1
Aminotransferase, class I/II; KEGG: cac:CAC2832 4.3e-108 PLP-dependent aminotransferase K00811; Psort location: Cytoplasmic, score: 8.87.
  
 0.824
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.792
Your Current Organism:
Catonella morbi
NCBI taxonomy Id: 592026
Other names: C. morbi ATCC 51271, Catonella morbi ATCC 51271, Catonella morbi str. ATCC 51271, Catonella morbi strain ATCC 51271
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