STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (170 aa)    
Predicted Functional Partners:
purD
KEGG: tte:TTE0593 1.2e-110 purD; phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 8.87; Belongs to the GARS family.
 
 0.999
ESL01675.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: tte:TTE0590 3.4e-99 purM; Phosphoribosylaminoimidazol (AIR) synthetase K01933; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.998
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.998
purC
KEGG: gsu:GSU2091 2.0e-78 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.87; Belongs to the SAICAR synthetase family.
 
 
 0.996
ESL04197.1
KEGG: sfu:Sfum_0268 1.6e-131 amidophosphoribosyltransferase K00764; Psort location: Cytoplasmic, score: 8.87; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.986
ESL02757.1
Adenylosuccinate lyase; KEGG: cno:NT01CX_2118 1.5e-174 purB; adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.975
ESL02932.1
AICARFT/IMPCHase bienzyme; KEGG: xtr:448061 4.5e-120 atic; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase K00602:K01492; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.955
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.863
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
   
 0.785
Your Current Organism:
Catonella morbi
NCBI taxonomy Id: 592026
Other names: C. morbi ATCC 51271, Catonella morbi ATCC 51271, Catonella morbi str. ATCC 51271, Catonella morbi strain ATCC 51271
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