Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DDD_3208Transmembrane metalloprotease M48, Ste24p. (414 aa)    
Predicted Functional Partners:
spoU
tRNA/rRNA methyltransferase.
       0.781
DDD_3209
Hypothetical protein.
       0.773
DDD_3206
Hypothetical protein.
     
 0.730
DDD_3205
Small mechanosensitive ion channel.
       0.727
ftsH
AAA-metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.670
djlA
DnaJ-like protein DjlA.
 
 
 0.598
DDD_3210
Hypothetical protein.
       0.592
DDD_3204
Putative oxidoreductase.
       0.520
grpE
Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]
  
  
 0.426
Your Current Organism:
Nonlabens dokdonensis
NCBI taxonomy Id: 592029
Other names: Donghaeana dokdonensis DSW-6, N. dokdonensis DSW-6, Nonlabens dokdonensis DSW-6, Nonlabens dokdonensis str. DSW-6, Nonlabens dokdonensis strain DSW-6, Persicivirga dokdonensis DSW-6
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