STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)    
Predicted Functional Partners:
EEU03598.1
Bacterial transferase hexapeptide repeat protein; KEGG: tte:TTE2572 8.8e-53 glmU; glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase K04042:K00972; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.941
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
 
 0.925
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.896
pth
aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
   0.867
rpiB
KEGG: aae:aq_1138 3.8e-36 rpiB; ribose 5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.87.
    
 0.862
EEU03898.1
Hydrolase, NUDIX family; KEGG: tte:TTE1310 2.9e-31 mutT2; NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.850
EEU03089.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: lmf:LMOf2365_1901 1.7e-97 phosphoglucomutase/phosphomannomutase family protein K01840; Psort location: Cytoplasmic, score: 8.87.
  
 0.841
EEU03488.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: cno:NT01CX_1776 2.1e-74 phosphomannomutase K01840; Psort location: Cytoplasmic, score: 8.87.
  
 0.834
EEU03886.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: cno:NT01CX_1267 1.8e-86 transketolase, N-terminal subunit K00615; Psort location: Cytoplasmic, score: 8.87.
    
  0.823
EEU03887.1
Transketolase, pyridine binding domain protein; KEGG: chy:CHY_0166 8.8e-85 putative transketolase, C-terminal subunit K00615; Psort location: Cytoplasmic, score: 8.87.
    
  0.823
Your Current Organism:
Eubacterium saphenum
NCBI taxonomy Id: 592031
Other names: E. saphenum ATCC 49989, Eubacterium saphenum ATCC 49989, Eubacterium saphenum str. ATCC 49989, Eubacterium saphenum strain ATCC 49989
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.