STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citACitrate-proton symporter; Is involved in the uptake of citrate and the transport of protons into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)    
Predicted Functional Partners:
tcuB
With CitA (TcuA) catalyzes the oxidation of tricarballylate to cis-aconitate; originally thought to be involved in citrate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.925
cobZ
Catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.625
dcuS
Histidine kinase; C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.619
rpmE2
50S ribosomal protein L31; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.616
ulaA_1
PTS ascorbate transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.613
rpmJ
50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.594
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
   
    0.589
ANA29532.1
Riboflavin synthase subunit alpha; Catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.542
nanT_2
Sialic acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.508
tcuR
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
    0.439
Your Current Organism:
Salmonella enterica diarizonae
NCBI taxonomy Id: 59204
Other names: ATCC 43973, CCUG 30040, CIP 82.31, DSM 14847, NCTC 10060, S. enterica subsp. diarizonae, Salmonella cholerae-suis subsp. diarizonae, Salmonella choleraesuis subsp. diarizonae, Salmonella enterica IIIb, Salmonella enterica serovar IIIb, Salmonella enterica subsp. IIIb, Salmonella enterica subsp. Subsp. IIIb, Salmonella enterica subsp. diarizonae
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.