STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaI4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde. (264 aa)    
Predicted Functional Partners:
hpaH
2-oxo-hepta-3-ene-1,7-dioate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
gabD
Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.989
ANA29184.1
5-carboxymethyl-2-hydroxymuconate delta-isomerase; Catalyzes the formation of 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid from 5-carboxymethyl-2-hydroxy-muconic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.970
ANA28268.1
Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.968
hpaD
3,4-dihydroxyphenylacetate 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.964
hpaX
4-hydroxyphenylacetate permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.823
hpaA
4-hydroxyphenylacetate catabolism regulator HpaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.810
hpaG
4-hydroxyphenylacetate degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.808
hpaE
Betaine-aldehyde dehydrogenase; Catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.703
hpaR
Homoprotocatechuate degradative operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.687
Your Current Organism:
Salmonella enterica diarizonae
NCBI taxonomy Id: 59204
Other names: ATCC 43973, CCUG 30040, CIP 82.31, DSM 14847, NCTC 10060, S. enterica subsp. diarizonae, Salmonella cholerae-suis subsp. diarizonae, Salmonella choleraesuis subsp. diarizonae, Salmonella enterica IIIb, Salmonella enterica serovar IIIb, Salmonella enterica subsp. IIIb, Salmonella enterica subsp. Subsp. IIIb, Salmonella enterica subsp. diarizonae
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