STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANA31758.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (887 aa)    
Predicted Functional Partners:
cas5e
Cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
cas7e
CRISPR-associated protein Cse4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
casA
CRISPR-associated protein CasA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
casB
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.993
ANA30889.1
ssRNA endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.989
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.989
cas6e
CRISPR-associated protein Cas6; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.989
tas
Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.875
Your Current Organism:
Salmonella enterica diarizonae
NCBI taxonomy Id: 59204
Other names: ATCC 43973, CCUG 30040, CIP 82.31, DSM 14847, NCTC 10060, S. enterica subsp. diarizonae, Salmonella cholerae-suis subsp. diarizonae, Salmonella choleraesuis subsp. diarizonae, Salmonella enterica IIIb, Salmonella enterica serovar IIIb, Salmonella enterica subsp. IIIb, Salmonella enterica subsp. Subsp. IIIb, Salmonella enterica subsp. diarizonae
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