STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gudDGlucarate dehydratase; Catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)    
Predicted Functional Partners:
garL
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
 
 
 0.999
garD
Galactarate dehydrogenase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.
 
 
 0.998
ANA30911.1
Glucarate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.901
glxK_1
Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.
  
  
 0.771
ANA29228.1
Galactarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.588
hycA
Formate hydrogenlyase regulatory protein HycA; Regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.572
hpaI
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
 
 
 0.530
garR
Tartronate semialdehyde reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
  
 0.495
rspA
Bifunctional D-altronate/D-mannonate dehydratase; Starvation-sensing protein; maybe involved in homoserine lactone degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.486
uxaA
Altronate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.469
Your Current Organism:
Salmonella enterica diarizonae
NCBI taxonomy Id: 59204
Other names: ATCC 43973, CCUG 30040, CIP 82.31, DSM 14847, NCTC 10060, S. enterica subsp. diarizonae, Salmonella cholerae-suis subsp. diarizonae, Salmonella choleraesuis subsp. diarizonae, Salmonella enterica IIIb, Salmonella enterica serovar IIIb, Salmonella enterica subsp. IIIb, Salmonella enterica subsp. Subsp. IIIb, Salmonella enterica subsp. diarizonae
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