STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA40694.1Helix-turn-helix domain-containing protein. (100 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.757
SEA41251.1
Cystathionine beta-lyase.
  
 
 0.723
SEA02978.1
Threonine dehydratase.
    
  0.702
SEA40722.1
Serine/threonine-protein kinase HipA.
       0.679
SEA60082.1
XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.517
SEA08048.1
Aspartate aminotransferase.
    
  0.516
SDZ76931.1
Sulfite reductase (NADPH) hemoprotein beta-component.
     
 0.512
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.508
SEA97782.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
    
 0.501
SEA40666.1
Topoisomerase DNA binding C4 zinc finger.
       0.495
Your Current Organism:
Acidovorax soli
NCBI taxonomy Id: 592050
Other names: A. soli, Acidovorax soli Choi et al. 2010, Acidovorax sp. BL21, DSM 25157, JCM 15909, KCTC 22399, strain BL21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.