STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA48995.1Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. (232 aa)    
Predicted Functional Partners:
SDZ99512.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
  
 
 0.996
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
 
 0.913
SEA49019.1
HAD-superfamily subfamily IB hydrolase, TIGR01490.
      0.886
SDZ92731.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
   
 
 0.820
pcnB
poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
 
 
 0.728
SDZ72915.1
LSU ribosomal protein L31P; Belongs to the bacterial ribosomal protein bL31 family.
  
    0.727
SEA07829.1
D-sedoheptulose 7-phosphate isomerase.
   
 
 0.686
SEA49069.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase.
     
 0.673
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
  
  
 0.671
SEA01312.1
Chromosome partitioning protein.
 
 
 0.593
Your Current Organism:
Acidovorax soli
NCBI taxonomy Id: 592050
Other names: A. soli, Acidovorax soli Choi et al. 2010, Acidovorax sp. BL21, DSM 25157, JCM 15909, KCTC 22399, strain BL21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.