STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (342 aa)    
Predicted Functional Partners:
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
 
 0.996
ilvA
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 0.908
ADU67935.1
TIGRFAM: threonine synthase; KEGG: eta:ETA_07000 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
     
 0.900
ADU68625.1
Threonine aldolase; KEGG: ctu:Ctu_14810 low specificity L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase.
     
  0.900
ADU69279.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: similar to oxidoreductase, short chain dehydrogenase/reductase family, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.900
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
  
 0.633
ADU71188.1
PFAM: glycosyl transferase group 1; KEGG: spe:Spro_4834 glycosyl transferase group 1.
  
  
 0.572
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
  
  
 0.503
ADU69342.1
KEGG: ecy:ECSE_1461 putative oxidoreductase Fe-S subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding.
     
 0.496
ADU71184.1
KEGG: sfv:SFV_3908 ADP-heptose:LPS heptosyltransferase II; TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9.
       0.455
Your Current Organism:
Pantoea sp. At9b
NCBI taxonomy Id: 592316
Other names: P. sp. At-9b, Pantoea sp. At-9b
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.