Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
mbc1AMembrane bound complex 1, subunit A (Mbc1A); 13 probable transmembrane helices predicted by modhmm. (525 aa)    
Predicted Functional Partners:
mbc1D
Membrane bound complex 1, subunit D (Mbc1D); 6 probable transmembrane helices predicted by modhmm.
  
 
 0.940
mhy2F
Formate hydrogenlyase II subunit F (Mhy2F).
 
 
 0.931
mbc1C
Membrane bound complex 1, subunit C (Mbc1C); 3 probable transmembrane helices predicted by modhmm.
  
 
 0.907
mbc1B
Membrane bound complex 1, subunit B (Mbc1B); 3 probable transmembrane helices predicted by modhmm.
  
 
 0.906
mhy2C1
Formate hydrogenlyase II subunit C (Mhy2C1); 14 probable transmembrane helices predicted by modhmm.
 
 
0.906
mbc1F
Membrane bound complex 1, subunit F (Mbc1F); 3 probable transmembrane helices predicted by modhmm.
  
 
 0.899
mbc1G
Membrane bound complex 1, subunit G (Mbc1G); 3 probable transmembrane helices predicted by modhmm.
  
 
 0.881
mhy2E
Formate hydrogenlyase II subunit E (Mhy2E); 7 probable transmembrane helices predicted by modhmm.
 
 
 0.871
mbhG
Membrane bound hydrogenase, MbhG subunit (MbhG); 3 probable transmembrane helices predicted by modhmm.
 
 
 0.864
mbhE
Membrane bound hydrogenase, MbhE subunit (MbhE); 2 probable transmembrane helices predicted by modhmm.
 
 
 0.861
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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