Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mhy2AFormate hydrogenlyase II subunit A (Mhy2A). (716 aa)    
Predicted Functional Partners:
mhy2B
Formate hydrogenlyase II subunit B (Mhy2B); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 0.992
fdh1B
Formate dehydrogenase I subunit B (fdh1B).
  
 0.967
TGAM_0823
7Fe ferredoxin.
  
 0.965
focA
Formate transporter (focA); 8 probable transmembrane helices predicted by modhmm.
 
  
 0.923
cooS
Carbon monoxide dehydrogenase (cooS).
     
 0.909
fdh1A
Formate dehydrogenase I subunit A (fdh1A).
  
  
 
0.905
fdhA
Formate dehydrogenase alpha subunit (fdhA); 2 probable transmembrane helices predicted by modhmm.
  
  
 
0.904
nox
NADH oxidase (NOXase) (nox).
    
 0.837
mhy2F
Formate hydrogenlyase II subunit F (Mhy2F).
  
  
 0.818
mhy2G
Formate hydrogenlyase II subunit G (Mhy2G).
  
  
 0.812
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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