Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdpMembrane dipeptidase (mdp). (312 aa)    
Predicted Functional Partners:
TGAM_0105
TRP-repeat-containing protein.
       0.914
TGAM_1057
Peptidase C26; Belongs to Class-I Glutamine amidotransferase superfamily.
     0.887
TGAM_0104
Conserved archaeal hypothetical protein.
       0.843
TGAM_0103
Signal peptidase, peptidase S26B; 1 probable transmembrane helix predicted by modhmm.
       0.823
TGAM_0107
Conserved hypothetical protein; Belongs to DUF257 family.
       0.782
TGAM_0109
SAM-dependent methyltransferase.
       0.649
TGAM_1587
Zinc-dependent metallopeptidase, putative; Contains zinc-binding region signature (PS00142).
 
 
 0.415
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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