close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_0109SAM-dependent methyltransferase. (281 aa)    
Predicted Functional Partners:
TGAM_0108
RecA family AAA ATPase; Contains 1 P_Loop (SSF52540) domain and 2 RecA (PR00142) domains.
       0.614
TGAM_1292
CRISPR-associated autoregulator, DevR family; Belongs to DUF73 family. Contains 1 Nucleic acid-binding, OB-fold.
  
     0.509
TGAM_0447
Conserved hypothetical protein; Contains DUF505 domain.
  
     0.504
TGAM_0465
RNA-binding protein, putative; Contains THUMP domain.
  
     0.446
TGAM_0933
Conserved hypothetical protein; Contains 1 Histone-fold (SSF47113) domain.
  
     0.432
TGAM_0150
P-loop ATPase, MJ1599 type.
 
     0.416
TGAM_1194
RNA-binding protein, putative; Contains CRS1 / YhbY domain.
  
     0.401
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: medium (44%) [HD]