Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pitAPhosphate permease, pho4/PitA-like protein (pitA/pho4); 12 probable transmembrane helices predicted by modhmm. (406 aa)    
Predicted Functional Partners:
TGAM_0118
Phosphate transport phoU/Pit related protein, putative.
 
  
 0.983
TGAM_0321
Phosphate transport regulator, putative; Belongs to DUF47 family, PhoU/Pit related.
 
  
 0.796
TGAM_2124
Metallophosphoesterase, calcineurin superfamily; 1 probable transmembrane helix predicted by modhmm.
       0.649
cpkA
Carbamate kinase (Carbamate kinase-like carbamoylphosphate synthetase) (cpkA).
       0.597
TGAM_2125
Conserved hypothetical protein; Contains 1 Cupin, RmlC-type domain.
       0.593
arcTGT
Archaeosine tRNA-guanine transglycosylase (ArcTGT); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.470
TGAM_1855
Amino acid transporter; 12 probable transmembrane helices predicted by modhmm.
  
  
 0.429
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (HisI); In the N-terminal section; belongs to the PRA-CH family.
     
 0.418
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.