| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TGAM_0121 | fbp | TGAM_0121 | TGAM_0123 | Oxidoreductase; Contains FAD/NAD(P)-binding domain, Aromatic-ring hydroxylase (flavoprotein monooxygenase) and adrenodoxin reductase family signatures. | Fructose-1,6-bisphosphatase (FBPase V) (fbp); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.453 |
| TGAM_0121 | gap | TGAM_0121 | TGAM_1667 | Oxidoreductase; Contains FAD/NAD(P)-binding domain, Aromatic-ring hydroxylase (flavoprotein monooxygenase) and adrenodoxin reductase family signatures. | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | 0.401 |
| TGAM_0121 | gor | TGAM_0121 | TGAM_0122 | Oxidoreductase; Contains FAD/NAD(P)-binding domain, Aromatic-ring hydroxylase (flavoprotein monooxygenase) and adrenodoxin reductase family signatures. | Glyceraldehyde-3-phosphate (GAP):ferredoxin oxidoreductase (gor). | 0.816 |
| apgM | deoC | TGAM_0731 | TGAM_0176 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.800 |
| apgM | fba | TGAM_0731 | TGAM_1754 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Fructose 1,6-bisphosphate aldolase class 1 (fba). | 0.873 |
| apgM | fbp | TGAM_0731 | TGAM_0123 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Fructose-1,6-bisphosphatase (FBPase V) (fbp); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.908 |
| apgM | gap | TGAM_0731 | TGAM_1667 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | 0.792 |
| apgM | gor | TGAM_0731 | TGAM_0122 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Glyceraldehyde-3-phosphate (GAP):ferredoxin oxidoreductase (gor). | 0.900 |
| apgM | pgiA | TGAM_0731 | TGAM_1078 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Glucose-6-phosphate isomerase, archaeal (pgiA); Belongs to the archaeal-type GPI family. | 0.873 |
| apgM | pgk | TGAM_0731 | TGAM_1318 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Phosphoglycerate kinase (pgk); Belongs to the phosphoglycerate kinase family. | 0.950 |
| apgM | tpiA | TGAM_0731 | TGAM_0313 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.787 |
| apgM | ttuD | TGAM_0731 | TGAM_1557 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Hydroxypyruvate reductase (ttuD). | 0.900 |
| deoC | apgM | TGAM_0176 | TGAM_0731 | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.800 |
| deoC | fba | TGAM_0176 | TGAM_1754 | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Fructose 1,6-bisphosphate aldolase class 1 (fba). | 0.914 |
| deoC | fbp | TGAM_0176 | TGAM_0123 | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Fructose-1,6-bisphosphatase (FBPase V) (fbp); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.908 |
| deoC | gap | TGAM_0176 | TGAM_1667 | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (gap). | 0.869 |
| deoC | gor | TGAM_0176 | TGAM_0122 | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Glyceraldehyde-3-phosphate (GAP):ferredoxin oxidoreductase (gor). | 0.800 |
| deoC | pgiA | TGAM_0176 | TGAM_1078 | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Glucose-6-phosphate isomerase, archaeal (pgiA); Belongs to the archaeal-type GPI family. | 0.811 |
| deoC | tpiA | TGAM_0176 | TGAM_0313 | Deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA) (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.896 |
| fba | apgM | TGAM_1754 | TGAM_0731 | Fructose 1,6-bisphosphate aldolase class 1 (fba). | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (apgM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.873 |