STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atpAArchaeal/vacuolar-type H+-ATPase subunit A (atpA); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (585 aa)    
Predicted Functional Partners:
atpI
Archaeal/vacuolar-type H+-ATPase subunit I (atpI); 7 probable transmembrane helices predicted by modhmm; Belongs to the V-ATPase 116 kDa subunit family.
 
 0.999
atpK
Archaeal/vacuolar-type H+-ATPase, subunit K (atpK); 4 probable transmembrane helices predicted by modhmm.
 
 0.999
atpE
Archaeal/vacuolar-type H+-ATPase, subunit E (atpE); Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpC
Archaeal/vacuolar-type H+ ATPase, subunit C (atpC); Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpF
Archaeal/vacuolar-type H+-ATPase, subunit F (atpF); Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.999
atpB
Archaeal/vacuolar-type H+-ATPase, subunit B (atpB); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
 
0.999
atpD
Archaeal/vacuolar-type H+-ATPase, subunit D (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpH
Archaeal/vacuolar-type H+-ATPase subunit H (atpH).
    
 0.986
ppa
Inorganic pyrophosphatase (ppa); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.928
TGAM_0149
Alanyl-tRNA synthetase-related protein (C-terminus).
  
    0.806
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.