Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0179Pyridoxal phosphate-dependent aminotransferase, class III family; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)    
Predicted Functional Partners:
mfnA
L-tyrosine decarboxylase (mfnA); Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
  
 0.937
TGAM_0307
Pyridoxal phosphate-dependent aminotransferase, class III family; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.905
TGAM_0403
Conserved hypothetical protein; Contains DUF137 domain.
     
  0.900
TGAM_0178
Conserved hypothetical protein; Predicted membrane protein; 6 probable transmembrane helices predicted by modhmm.
       0.818
trxB
Thioredoxin reductase (trxB); 1 probable transmembrane helix predicted by modhmm.
     
 0.817
TGAM_0181
Conserved hypothetical protein; Belongs to DUF457 family, predicted membrane-bound metal-dependent hydrolase; 3 probable transmembrane helices predicted by modhmm.
     
 0.753
TGAM_0182
AAA family ATPase, possibly ruvB related.
       0.751
TGAM_0183
RNA-binding protein, putative; Contains 1 THUMP domain.
       0.607
argE
Acetyl ornithine deacetylase related protein (argE).
  
 0.575
TGAM_1726
Dioxygenase, putative; Contains LigB subunit of an aromatic-ring-opening dioxygenase LigAB signature (SF53213); Belongs to the MEMO1 family.
   
 
  0.526
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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