Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0182AAA family ATPase, possibly ruvB related. (396 aa)    
Predicted Functional Partners:
TGAM_0183
RNA-binding protein, putative; Contains 1 THUMP domain.
 
     0.930
TGAM_0181
Conserved hypothetical protein; Belongs to DUF457 family, predicted membrane-bound metal-dependent hydrolase; 3 probable transmembrane helices predicted by modhmm.
     
 0.914
trxB
Thioredoxin reductase (trxB); 1 probable transmembrane helix predicted by modhmm.
     
 0.859
TGAM_0179
Pyridoxal phosphate-dependent aminotransferase, class III family; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.751
TGAM_1760
Replication factor A complex, RPA41 subunit; Subunit of the RPA hetero-oligomeric complex.
  
     0.663
TGAM_1748
Regulatory protein HTH/ArsR family, disease resistance-related, containing ATPase domain; Contains 3 TRP repeats.
 
     0.623
TGAM_2006
Regulatory protein HTH/ArsR family, disease resistance-related, containing ATPase domain; Contains 3 TRP repeats.
 
     0.611
TGAM_1498
Brix-domain ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.
  
     0.607
TGAM_0117
Protein kinase, putative; Contains protein kinase-like (SSF56112) domain.
  
     0.603
blaI
Penicillinase repressor-like protein (BlaI).
 
  
 0.596
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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