Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_0205Predicted AP endonuclease; May be also related to Xylose isomerase. (262 aa)    
Predicted Functional Partners:
pstC
ABC-type phosphate transport system, permease component (pstC); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
   
 0.911
pstA
ABC-type phosphate transport system, permease component (pstA); 5 probable transmembrane helices predicted by modhmm.
 
   
 0.911
pstB
ABC-type phosphate transport system, ATPase component (pstB); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.899
phoU-1
Phosphate ABC transporter, regulatory protein (phoU).
       0.878
pstS
ABC-type phosphate transport system, periplasmic component (PstS); 1 probable transmembrane helix predicted by modhmm; Belongs to the PstS family.
 
    0.769
hps
3-hexulose-6-phosphate synthase-6-phospho 3-hexuloisomerase fused bifuntional enzyme (hps).
 
    0.518
TGAM_0210
Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.505
TGAM_0211
Hypothetical protein; 2 probable transmembrane helices predicted by modhmm.
       0.505
TGAM_0202
SAM-dependent RNA methylase, putative; Belongs to UPF0020 family, contains 1 THUMP domain.
       0.501
TGAM_0203
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.499
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.