Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0216Transcription regulatory membrane protein, HTH-AraC family; 10 probable transmembrane helices predicted by modhmm. (281 aa)    
Predicted Functional Partners:
TGAM_0217
Metallo-beta-lactamase superfamily protein; Possibly related to Ribonuclease Z.
 
     0.927
TGAM_0214
Conserved hypothetical protein; Belongs to DUF104 family.
       0.683
vapC
Nucleotide binding protein, putative, containing PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.634
trpS
Tryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp).
  
    0.555
TGAM_0213
Prokaryotic ATPase, AAA superfamily; Contains Archaeal ATPase domain (PF01637).
       0.477
TGAM_0326
TRP-repeat-containing protein; 4 probable transmembrane helices predicted by modhmm.
 
 
 0.441
TGAM_0406
Oligosaccharyl transferase STT3 subunit; 10 probable transmembrane helices predicted by modhmm.
  
   0.408
TGAM_1749
Conserved hypothetical protein; Possibly a cell adhesion protein. Contains 9 APHP/CARDB and 2 PKD domains; 1 probable transmembrane helix predicted by modhmm.
  
     0.407
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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