Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acsAAcetyl-coenzyme A synthetase (acsA). (646 aa)    
Predicted Functional Partners:
TGAM_0460
Acetyl-CoA C-acetyltransferase.
  
 
 0.958
porG
Pyruvate/ketoisovalerate oxidoreductases common gamma subunit (porG).
  
 
 0.925
TGAM_0317
Coenzyme A transferase.
    
 0.922
porA
Pyruvate synthase subunit porA (pyruvate oxidoreductase alpha chain) (pyruvate ferredoxin oxidoreductase) (porA).
  
 
 0.918
korA-1
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA).
  
 
 0.918
korA-2
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA).
  
 
 0.918
porB
Pyruvate synthase subunit porB (pyruvate oxidoreductase beta chain) (pyruvate ferredoxin oxidoreductase) (porB).
  
 
 0.916
porD
Pyruvate synthase subunit porD (pyruvate oxidoreductase delta chain) (pyruvate ferredoxin oxidoreductase) (porD).
  
 
 0.916
korB-1
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB).
  
 
 0.916
korB-2
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB); 2 probable transmembrane helices predicted by modhmm.
  
 
 0.916
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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