Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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nikRTranscription nickel responsive regulator (nikR); Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (138 aa)    
Predicted Functional Partners:
hypA
[NiFe] hydrogenase maturation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.691
TGAM_1812
Conserved hypothetical protein.
       0.649
TGAM_1714
Hypothetical protein; Contains C-term (DUF814) and N-term (PF05833) domains as in O34693; 4 probable transmembrane helices predicted by modhmm.
       0.616
TGAM_0234
PP-loop ATPase, mrp-like protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.613
cooC-1
CODH nickel-insertion accessory protein, CO dehydrogenase maturation factor (cooC).
       0.595
mntB
Manganese ABC-type transporter ATP-binding protein (mntB).
     
 0.407
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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