Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM_0237Conserved hypothetical protein. (91 aa)    
Predicted Functional Partners:
TGAM_0238
Conserved hypothetical protein.
       0.914
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A (mobA); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
       0.738
TGAM_0240
Nucleotidyltransferase, putative.
       0.681
mhy2I-2
Putative formate hydrogenlyase I subunit I (Mhy2I).
       0.588
mhy1H
Formate hydrogenlyase I subunit H (Mhy1H); 1 probable transmembrane helix predicted by modhmm.
       0.588
mhy1E
Formate hydrogenlyase I subunit E (Mhy1E); 7 probable transmembrane helices predicted by modhmm.
       0.588
mhy1C
Formate hydrogenlyase I subunit C (Mhy1C); 14 probable transmembrane helices predicted by modhmm.
       0.582
mhy1F
Formate hydrogenlyase I subunit F (Mhy1F).
       0.580
mhy1G
Formate hydrogenlyase I subunit G (Mhy1G).
       0.563
mhy1D
Formate hydrogenlyase I subunit D (Mhy1D); 16 probable transmembrane helices predicted by modhmm.
       0.560
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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