Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mhy1GFormate hydrogenlyase I subunit G (Mhy1G). (201 aa)    
Predicted Functional Partners:
mhy1F
Formate hydrogenlyase I subunit F (Mhy1F).
 
 0.992
mhy2F
Formate hydrogenlyase II subunit F (Mhy2F).
 
 0.969
mhy1H
Formate hydrogenlyase I subunit H (Mhy1H); 1 probable transmembrane helix predicted by modhmm.
 
 
 0.936
mhy1C
Formate hydrogenlyase I subunit C (Mhy1C); 14 probable transmembrane helices predicted by modhmm.
  
 
 0.930
mhy1E
Formate hydrogenlyase I subunit E (Mhy1E); 7 probable transmembrane helices predicted by modhmm.
 
 
 0.911
mbxJ
Membrane bound oxidoreductase, MbxJ subunit (MbxJ); Belongs to the complex I 20 kDa subunit family.
 
 0.865
mbxL
Membrane bound oxidoreductase, MbxL subunit (MbxL); Belongs to the complex I 49 kDa subunit family.
 
 0.862
mhy1D
Formate hydrogenlyase I subunit D (Mhy1D); 16 probable transmembrane helices predicted by modhmm.
  
 
 0.821
mbxK
Membrane bound oxidoreductase, MbxK subunit (MbxK).
 
 0.795
mhy2I-2
Putative formate hydrogenlyase I subunit I (Mhy2I).
       0.782
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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