Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
porAPyruvate synthase subunit porA (pyruvate oxidoreductase alpha chain) (pyruvate ferredoxin oxidoreductase) (porA). (394 aa)    
Predicted Functional Partners:
porB
Pyruvate synthase subunit porB (pyruvate oxidoreductase beta chain) (pyruvate ferredoxin oxidoreductase) (porB).
 0.999
porD
Pyruvate synthase subunit porD (pyruvate oxidoreductase delta chain) (pyruvate ferredoxin oxidoreductase) (porD).
 
 0.999
vorB
Ketoisovalerate oxidoreductase subunit vorB (vorB).
 
 0.999
porG
Pyruvate/ketoisovalerate oxidoreductases common gamma subunit (porG).
 
 0.999
vorD
Ketoisovalerate oxidoreductase subunit vorD (vorD).
 
 
 0.989
korB-1
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB).
 
 0.975
korB-2
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB); 2 probable transmembrane helices predicted by modhmm.
 
 0.975
acsA
Acetyl-coenzyme A synthetase (acsA).
  
 
 0.918
TGAM_0460
Acetyl-CoA C-acetyltransferase.
  
 
 0.912
ppsA
Phosphoenolpyruvate synthase (pyruvate,water dikinase) (PEP synthase) (ppsA); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.910
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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