Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
porDPyruvate synthase subunit porD (pyruvate oxidoreductase delta chain) (pyruvate ferredoxin oxidoreductase) (porD). (105 aa)    
Predicted Functional Partners:
porB
Pyruvate synthase subunit porB (pyruvate oxidoreductase beta chain) (pyruvate ferredoxin oxidoreductase) (porB).
 
 0.999
porA
Pyruvate synthase subunit porA (pyruvate oxidoreductase alpha chain) (pyruvate ferredoxin oxidoreductase) (porA).
 
 0.999
porG
Pyruvate/ketoisovalerate oxidoreductases common gamma subunit (porG).
 
 0.999
vorB
Ketoisovalerate oxidoreductase subunit vorB (vorB).
 
 
 0.992
vorA
Ketoisovalerate oxidoreductase subunit vorA (vorA).
 
 
 0.990
korB-1
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB).
  
 0.957
korA-1
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA).
  
 0.957
korB-2
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB); 2 probable transmembrane helices predicted by modhmm.
  
 0.957
korA-2
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA).
  
 0.957
pyk
Pyruvate kinase (pyk); Belongs to the pyruvate kinase family.
    
 0.938
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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