Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGAM_0276Histone acetyltransferase-like protein; Contains Elp3 (Elongator protein 3), belongs to GNAT methyltransferases family. (589 aa)    
Predicted Functional Partners:
TGAM_0279
Ribosome subunit biogenesis protein, putative; Belongs to UPF0113 family.
  
    0.906
TGAM_0278
Conserved hypothetical protein; UPF0153 family.
       0.860
TGAM_0274
NIF3 (NGG1p interacting factor 3)-like protein.
       0.834
TGAM_0277
Conserved hypothetical protein; 1 probable transmembrane helix predicted by modhmm.
       0.669
TGAM_0925
Met-10 like-protein, putative SAM-dependent methyltransferase.
 
  
 0.647
tuf
Elongation factor 1-alpha (EF-1-alpha) (Elongation factor Tu) (EF-Tu) (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
    
   0.646
ksgA
Ribosomal RNA adenine methylase transferase (Dimethyladenosine transferase) (ksgA); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.621
TGAM_0020
PP-loop ATPase, YdaO-type.
  
 
 0.619
TGAM_0852
Nonsense-mediated mRNA decay protein, NMD3-like protein.
   
  
 0.575
truA
tRNA-pseudouridine synthase A (truA); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
   
 
 0.569
Your Current Organism:
Thermococcus gammatolerans
NCBI taxonomy Id: 593117
Other names: T. gammatolerans EJ3, Thermococcus gammatolerans EJ3, Thermococcus gammatolerans str. EJ3, Thermococcus gammatolerans strain EJ3
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